Ca-AKG: Real Benefits in 2025

Calcium Alpha-Ketoglutarate (Ca-AKG, CAS: 71686-01-6) is a stabilized form of alpha-ketoglutarate with ~99% purity, widely recognized in nutritional and sports supplements. As a key intermediate in the Krebs (TCA) cycle, Ca-AKG supports energy production, amino acid synthesis, and cellular health. Its calcium-bound form enhances stability and bioavailability, making supplementation more effective.

Core Benefits of Ca-AKG

- Bone Health Support
  Enhances calcium utilization, increases bone density, and slows age-related bone loss.

- Energy & Endurance
  Fuels ATP production for muscles and the heart, helping reduce fatigue and boost stamina.

- Inflammation Balance
  Helps regulate cytokines, lowering markers linked to chronic conditions like diabetes and metabolic syndrome.

- Longevity & Cellular Renewal
  Promotes autophagy (cellular cleanup) and activates AMPK for energy balance and healthy blood sugar control.

- Brain Health
  Serves as a glutamate precursor, supporting neurotransmission and reducing oxidative stress—factors tied to memory and cognitive resilience.

Ca-AKG vs. AKG: Key Differences

- AKG (alpha-ketoglutarate): Supports energy metabolism and amino acid synthesis.

- Ca-AKG (calcium salt): Offers the same benefits plus added calcium for bone and cellular health.

- Use Cases: AKG is common in sports and antioxidant supplements; Ca-AKG is more suited for bone support and healthy aging.

How to Source Ca-AKG

Choose a Trusted Supplier
Select a GMP/ISO-certified producer like Hydebio Labs, providing HPLC-verified purity (≥99%).
Order Flexibly
- Samples: Small packs for R&D
- Bulk Supply: From 1kg to ton-scale
- Private Label / OEM: Tailored capsules or powders
Check Regulations
Ensure compliance with local dietary supplement laws before procurement.
Do Your Research
Review specifications, studies, and safety guidelines for informed use.

Disclaimer

This article is for informational purposes only and does not provide medical advice. Always consult a healthcare professional before using supplements or altering your health regimen.